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Guinea Pigs (Laboratory) - Pathology (view source)
Revision as of 21:02, 6 November 2010
, 21:02, 6 November 2010→Pregnancy toxaemia
===Pregnancy toxaemia===
===Pregnancy toxaemia===
Pregnancy toaemia is a metabolic disorder similar to twin lamb disease in sheep. Predisposing factors include obesity and stress leading to negative energy balance. The energy imbalance progresses to ketoacidosis together with aciduria, proteinuria and hyperlipaemia. There is also a fatty degeneration of the liver. <br />
Pregnancy toaemia is a metabolic disorder similar to twin lamb disease in sheep. Predisposing factors include obesity and stress leading to negative energy balance. The energy imbalance progresses to ketoacidosis together with aciduria, proteinuria and hyperlipaemia. There is also a fatty degeneration of the liver. <br />
In cases of stress the sow stops eating, becomes depressed and will have a ruffled appearance. Some sows may also salivate profusely and the distinctive smell of ketones (pear drops) may be present. The condition is more prevalent in hot weather.<br />
In cases of stress the sow stops eating, becomes depressed and will have a ruffled appearance. Some sows may also salivate profusely and the distinctive smell of ketones (pear drops) may be present. The condition is more prevalent in hot weather.<br />
Necropsy will show an empty stomach and pathology including fatty liver and kidneys, fetae with varying levels of haemorrhage and large fat reserves in the abdomen.
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===Miscarriage and Abortion===
===Miscarriage and Abortion===
If abortion occurs early in gestation (up to 40 days) the sow will commonly not be systemically affected. Later than 40 days will result in systemic illness with severe blood loss with potentially fatal consequences. <br />
If abortion occurs early in gestation (up to 40 days) the sow will commonly not be systemically affected. Later than 40 days will result in systemic illness with severe blood loss with potentially fatal consequences. <br />