Chocolate Poisoning-Dog



Introduction

Toxicity is due to the presence of methylxanthines such as theobromine and caffeine in chocolate. They are also present in stimulant preparations and other products.[1]

Signalment

Dog that live indoors are more likely to have access to chocolate.[1]


Diagnosis

Clinical Signs

Chocolate poisoning results in CNS, gastrointestinal and cardiovascular signs.[1]

  • CNS: hyperexcitability, hyperactivity, ataxia initially can evolve into muscle tremors, clonic seizures and hyperthermia.[1], [1]
  • Gastrointestinal: diarrhoea, emesis, haematemesis, colic.[1], [1]
  • Cardiovascular: arrhythmias,infrequently bradycardia but usually tachycardia.[1], [1]

Laboratory Tests

Pathology

The methylxanthines yield their effects through

  • Antagonism of Adenosine Receptors:[1]
  • Inhibition of Cyclic Nucleotide Phosphodiesterase:[1]

Treatment

Prognosis

References

  1. 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 BSAVA Manual of Canine and Feline Emergency and Critical CareSecond Edition,2007 Cite error: Invalid <ref> tag; name "multiple" defined multiple times with different content Cite error: Invalid <ref> tag; name "multiple" defined multiple times with different content Cite error: Invalid <ref> tag; name "multiple" defined multiple times with different content Cite error: Invalid <ref> tag; name "multiple" defined multiple times with different content Cite error: Invalid <ref> tag; name "multiple" defined multiple times with different content Cite error: Invalid <ref> tag; name "multiple" defined multiple times with different content Cite error: Invalid <ref> tag; name "multiple" defined multiple times with different content Cite error: Invalid <ref> tag; name "multiple" defined multiple times with different content Cite error: Invalid <ref> tag; name "multiple" defined multiple times with different content Cite error: Invalid <ref> tag; name "multiple" defined multiple times with different content

[1] [2]

  1. Tilley SmithThe 5-Minute Veterinary Consult Canine and Feline (Second Edition), Lippincott, Williams and Wilkins
  2. BSAVA Manual of Canine and Feline Emergency and Critical Care Second Edition, 2007