Foetal Circulation - Anatomy & Physiology

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Foetal versus Adult Circulation

A large number of physiological processes that are necessary for the embryo’s survival, such as detoxification, gas exchange and waste removal, are carried out by the placenta [[1]] rendering organs such as the liver and lungs surplus to requirement. There are a number of foetal circulatory shunts that ensure oxygen and nutrient rich blood flows directly to the most important organs, namely the brain, heart and adrenal glands.

Shunt 1: The Ductus Venosus

Oxygenated blood travels from the placenta via the umbilical vein and most of it bypasses the liver by way of the ductus venosus. The ductus venosus links the umbilical vein to the caudal vena cava and the flow of blood is controlled by a sphincter, enabling the proportion travelling to the heart versus the liver to be altered.

Shunt 2: The Foramen Ovale

The foramen ovale is an opening between the two atria enabling blood to be channelled directly into the systemic circulation thereby bypassing the lungs. The septum secundum directs the majority of the blood entering the right atrium through the foramen ovale into the left atrium. Here it mixes with a small volume of blood returning from the non-functional lungs via the pulmonary veins.

Shunt 3: The Ductus Arteriosus