Glossitis, Ulcerative

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  • Cat
  • Relatively common.
  • Youngish to middle age (mainly - although can be any age).
  • Unable to eat although wants to. Hurts to open mouth.
  • Whole of back of mouth covered in ulcerative granulation tissue.
  • Chronic, tends to start at angle of jaw (bilateral), progression quite slow but over weeks affects whole of back of mouth.
  • May also affect anatomy and physiology of the tongue.

Pathology

Epithelium lost over whole of mucosa, lots of macrophages, lymphocytes and proliferating fibrous response at base.

Pathogenesis

  • Probably viral.
  • Calicivirus found in 7-80%, also often find picorna virus and Feline Immunodeficiency Virus
  • Probably calici virus that starts it.
  • Also owners often claim develops after 'having cold' prior to it.
  • Calici virus infection may be followed by autoimmune / exaggerated immune response which produces lesions.
  • Will heal eventually, but takes time and cat loses lots of condition.