Panosteitis

Panosteitis (Image sourced from Bristol Biomed Image Archive with permission)
  • Typically young large or giant breeds
  • 75% of cases in German shepherd dogs, 5-12 months old
  • Clinical signs:
    • Shifting lameness
    • Often eosinophilia in peripheral blood
  • Usually self-limiting in one to several months
  • Grossly:
    • Foreleg long bone diaphyses affected (multiple bones in 50% of cases)
    • Increased bone formation in the medullary cavity and often in the periosteum
  • Contast with hypertrophic osteodystrophy