Host Invasion by Microorganisms Flashcards

WIKIBLOOD FLASHCARDS

Host invasion

Question	Answer	Article
By what three routes can pathogens enter the body?	Contact Aerosol Orofecal	Link to Answer Article

Viruses

Question	Answer	Article
Naked viruses contain only...?	RNA/DNA and protein coat	Link to Answer Article
Name three functions of viral structural proteins	Protection of the genome Attachment to host cell Fusion of envelope to host cell membrane	Link to Answer Article
Name the two main innate defences against viral infection	Interferon Natural killer cells	Link to Answer Article
Upon viral infection, which antibody isotype is increased at mucosal surfaces?	IgA	Link to Answer Article
What do antibodies stop free virus particles from doing?	Binding to host cell, entering and uncoating	Link to Answer Article
By what mechanism is complement able to damage the virion envelope?	Virolysis	Link to Answer Article
When coupled with antibodies, what mechanisms does complement aid in immune defence?	Blocking the virus receptor Lysis of infected cells Opsonisation of free particles or infected cells	Link to Answer Article
What are the main cytokines CD4+ T cells release to recruit macrophages?	IFN-γ TNF	Link to Answer Article