Caprine Arthritis Encephalitis Virus
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Antigenicity
- Serologically related to Visna-Maedi with antigenic and genetic envelope differences
Hosts
- Goats
Pathogenesis
- T cells induce immune complex disease
- Causes encephalitis of kids or insidious polyarthritis of adults
- Also causes pneumonia
Epidemiology
- Transfer via milk and colostrum, particularly batch-mixing
- Present in 10% of UK herds
- Clinical disease is rare
Diagnosis
- Visna-Maedi serology (ELISA) test can be used to remove positive stock
Control
- Separate kids from virus positive mothers at birth
- Treat mother's colostrum (56 deg for 1 hour)
- Rear on artificial milk