Category:Liver - General Pathology

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Liver - General Pathology

  • The lobed liver is the largest gland in the body
  • A healthy liver is dark reddish-brown in colour with a smooth rubbery texture
  • Liver lesions are common because:
    • it is an area of high metabolic activity
    • receives toxic agents from the gut via the portal blood system
    • has an extensive vascular supply (prime site for metastatic disease)
  • Although liver lesions are common, they seldom produce liver failure
  • Diagnostic value because often indicates the presence and causes of disease in other organs and systems of the body


Liver response to injury

Liver Necrosis

Liver Regeneration

Liver Fibrosis

Biliary Hyperplasia

Cirrhosis


Molecular pathogenesis of cholestasis

Hepatic Stellate Cells