Infectious Pustular Vulvovaginitis

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Also known as IPV Caused by:Bovine Herpesvirus 1

venereal transfer

Pathogenesis

  • Painful genital lesions
  • Impaired reproductive performance
  • Frequent micturition

Diagnosis

  • Virus isolation and immunofluorescence

Control

  • Vaccination:
    • Two live attenuated vaccines are available in the UK, one is temperature-sensitive
      • Both given intranasally
      • Neither protect against re-infection when given during clinical outbreak, but can lessen the severity of the disease
    • Inactivated vaccines: intranasal/intramuscular administration
      • gE deletion makes this a marker vaccine
      • ELISA for gE deletion can enable culling of carrier animals
  • IPV has mostly been made obsolete by AI