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- Transmission via contact with secretions from infected animals
- Routes of infection: skin abrasions, inhalation, ingestion
- Unpasteurised milk source of infection
- Undulant fever - fluctuating pyrexia, malaise, fatigue, muscle and joint pains, osteomyelitis
- Can become chronic
- B melitensis and B. suis cause most severe infections
- Antimicrobials