Testicular Neoplasia

• TESTICULAR NEOPLASIA

Common in dog, may be multiple, bilateral with more than one tumour type within a testis. There is increased incidence of tumours (especially Sertoli cell tumours) in cryptorchid testes; these may be very large when identified. It is important to section spermatic cord to check for metastatic spread.

Germinal cells:

1. Teratoma:young stallion.
2. Seminoma:old dogs and stallions.

Sex cord-stroma:

1. Sertoli cell tumours:old dogs (more common than seminoma).
2. Leydig (Interstitial) cell tumours:old dogs commonly and bulls.

Classification of testicular tumours

insert table here

Feminisation syndrome associated with Sertoli cell tumours

Thus is due to oestrogen production and is seen as:
Skin:ventral alopecia and hyperpigmentation.
Mammary gland:cystic hyperplasia.
Genital organs:preputial oedema, squamous metaplasia of prostate (decreased size), contralateral testicular atrophy.

Information by kind permission of Professor R W Else