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Naked viruses contain only...?
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Name three functions of viral structural proteins
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- Protection of the genome
- Attachment to host cell
- Fusion of envelope to host cell membrane
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Name the two main innate defences against viral infection
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- Interferon
- Natural killer cells
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Upon viral infection, which antibody isotype is increased at mucosal surfaces?
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What do antibodies stop free virus particles from doing?
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- Binding to host cell, entering and uncoating
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By what mechanism is complement able to damage the virion envelope?
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When coupled with antibodies, what mechanisms does complement aid in immune defence?
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- Blocking the virus receptor
- Lysis of infected cells
- Opsonisation of free particles or infected cells
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What are the main cytokines CD4+ T cells release to recruit macrophages?
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