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Antifungals
Fungal infections are not uncommon in reptiles and can be the primary disease agent or secondary in already compromised individuals. Antifungal drugs may be useful but treatment regimens have not been established adequately.
Amphotericin-B
- Potentially nephrotoxic
- Can be used with ketaconazole
- Administer slowly
- 0.5 mg/kg IV q48-72h
- 5 mg/150ml saline x 1h nebulisation q12h 7d
Fluconazole
- 5 mg/kg PO q24h
Griseofulvin
- Limited success
- 20-40 mg/kg PO q72h 5 Rxs
Itraconazole
- Has been used in spiny lizards (Sceloporus spp.) at 23.5 mg/kg
Ketaconazole
- Potentially hepatotoxic
- 15-30 mg/kg PO q24h 2-4w
Nystatin
- 100,000 IU/kg PO q24h 2-4 w