Acute hepatoxicity
Almost invariably causes widespread haemorrhages in the body due to excessive consumption of the clotting factors in the damaged liver coupled with failure to produce these factors by the damaged liver.
Blue-green Algae
Iron
Cresols
- from tarred piggeries and clay pigeons
- produce massive necrosis in the liver of pigs
Clinical
- jaundice
- weakness
- coma
- death
NB: former use of carbon tetrachloride as an anthelmintic and phosphorous as a rodenticide has produced liver necrosis
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