• Inflammation of the bile ducts
  • ascending infections
    • common in cats
    • calves eg Salmonella sp.

Cats

      • cholangitis
      • periportal hepatocellular necrosis
      • neutrophils in the portal areas
      • acute or chronic.
      • Usually male, pure bred
      • Cats more ill than lymphocytic portal hepatitis.
      • Higher ALT and serum bilirubin levels.

Chronic lymphocytic cholangitis

  • mature cats

Microscopically

  • lymphocytic infiltration of the portal areas
  • mild fibrosis
  • biliary hyperplasia