• Caused by Brucella abortus
    • Eradicated in many countries including UK
    • Infection usually by ingestions but also venereal, skin abrasions, inhalation, transplacental
    • Abortion storms in susceptible herds
    • Abortion after fifth month of gestation due to placentitis
    • Brucellae excreted in foetal fluids for 2-4 weeks following abortion and at subsequent parturitions without abortion
    • Infection of mammary glands and lymph nodes persists for years
    • Excreted intermittently in milk for years
    • Seminal vesicles, ampullae, testicles and epididymus infected in bulls; necrotising orchitis
    • Decreased fertility in cows and bulls; decreased milk production
    • Localisation in spleen and lymphatic tissue of non-pregnant animals
    • Occasionally causes arthritis
  • Isolated from closed cases of poll evil and fistulous withers in horses