Lymphocytic Inflammation

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  • Lymphocytic inflammation is a diffuse chronic ongoing inflammation.
  • Seen in:
    1. Diseases of the central nervous system.
      • Lymphocytes appear microscopically as several layers of cells around blood vessels in the perivascular space.
      • They indicate that there is damage to the nervous tissue further in.
        • Should alert to the possibility of viral infection, which is a common cause of central nervous system disease.
          • E.g. louping ill.
    2. The gut.
      • An excessive number of lymphocytes diffusely infiltrating the lamina propria, often in conjunction with plasma cells, indicate an ongoing non-specific chronic enteritis.
    3. The respiratory tract.
      • Peribronchial and peribronchiolar cuffing may occur to the point of actual lymphoid follicle formation in these areas.
        • Follicles are sometimes large enough to cause partial occlusion of the airways.
      • A feature of some chronic lung diseases.