Causes Canine Infectious Tracheobronchitis
CH is caused by a nonenveloped DNA virus, canine adenovirus 1 (CAV-1), which is antigenically related only to CAV-2 (one of the causes of infectious canine tracheobronchitis, Infectious Tracheobronchitis of Dogs). CAV-1 is resistant to lipid solvents and survives outside the host for weeks or months, but a 1-3% solution of sodium hypochlorite (household bleach) is an effective disinfectant.
- Adenoviridae
- Usually mild bronchointerstitial pneumonia, necrosis of bronchiolar and alveolar epithelium, oedema, type II pneumocyte hyperplasia
- May cause necrotising bronchiolitis in immune-deficient dogs (distemper)
- Can be associated with kennel cough described above
Hosts
- Dogs
- Foxes are very susceptible (Fox Encephalitis)
Epidemiology
- Transfers easily via ingesting infected urine, feces or respiratory secretions
- Can be transferred by handlers, infected surfaces, etc.
