Category:Primary Immunodeficiency

Primary immunodeficiencies may affect either the innate immune system or the adaptive immune system. They are categorised by either the type or the developmental stage of the cells involved. Lymphoid cell disorders affect T cells or B cells (or both). Myeloid cell disorders affect phagocytic function. The severity of the immunodeficiency depends on at which stage in development the problem occurs. E.g. Defects early on in development will affect the entire immune system. T cell deficiencies can affect both the cell-mediated and humoral response as T cells play a central role in the immune system.