Lamb Dysentery

Description

• Clostridium perfringens causes very severe acute haemorrhagic enteritis.
  • Usually affects young farm animals
    • May also be seen in pets.
• Type B Clostridium perfringens infection of lambs leads to lamb dysentery.

• Lamb dysentery is usually seen in lambs under 2 weeks of age.
  • Related to being kept in a cold, dirty environment, with build-up of infection during the lambing season.
• Lambs may produce bloodstained diarrhoea before death, but they often die before this effect is apparent.
• Diagnosed by culturing contents of gut.

Infection with Clostridium perfringens types B and C causes severe enteritis, dysentery, toxemia, and high mortality in young lambs, calves, pigs, and foals. Types B and C both produce the highly necrotizing and lethal β toxin that is responsible for severe intestinal damage. This toxin is sensitive to proteolytic enzymes, and disease is associated with inhibition of proteolysis in the intestine. Sow colostrum, which contains a trypsin inhibitor, has been suggested as a factor in the susceptibility of young piglets. Type C also causes enterotoxemia in adult cattle, sheep, and goats. The diseases are listed below, categorized as to cause and host. C perfringens also has been associated with hemorrhagic enteritis in dogs. (See also intestinal diseases in horses, Intestinal Diseases in Horses and Foals: Introduction.) Lamb dysentery: type B in lambs up to 3 wk of age

Diagnosis

Pathology

• The gut is blown and distended with foamy ,bloody contents.
• Sometimes ulceration with perforation and fibrinousperitonitis is seen.
• Focal or diffuse congestion and haemorrhage

• Coagulative necrosis of villi.
• Oedema.
• Haemorrhage.
• Influx of inflammatory cells in the lamina propria and submucosa.