Ethylene Glycol Toxicity
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Introduction
Ethylene Glycol is a sweet tasting fluid that is the main component of anti-freeze. Consequently in colder climates ethylene glycol toxicity is frequently encountered in practice. It has a relatively low minimum lethal dose, and its sweet taste makes it attractive to dogs, cats and other small animals.
Signalment
Diagnosis
Clinical Signs
Laboratory Tests
Pathology
Treatment
Ethylene Glycol is a weak acid. Therefore in order to increase the rate of renal clearance sodium bicarbonate can be administered to dogs. Intravenous administration of sodium bicarbonate at a concentration of 1-2 mmol/kg every 3 to 6 hours achieves sufficient alkalinisation of the urine.[1]
Prognosis
References
- ↑ Canine Medicine and Therapeutics (Fourth Edition, 1998),Blackwell Science, p1049