Callus
- Hypertrophy of epidermis, particularly at pressure points
- Usually affects giant breed dogs and pigs kept on hard floor
- May be followed by folliculitis, furunculosis and ulceration
- Microscopically:
- Hyperkeratosis and acanthosis or epidermis and follicular epithelium
- Comedones and follicular cysts may be present, potentially rupture and cause secondary pyoderma
- Excessive keratin widening follicular openings