Epidermolysis Bullosa

Epidermolysis bullosa in a lamb (Courtesy of Bristol BioMed Image Archive)

• Also called Red Foot Disease
• Occurs in sheep, dogs, cattle and horses
• Development of cutaneous blisters
• Varies depending on hereditary cause
• Affected animals tend not to survive
• Lesions appear at surfaces that are easily damaged, e.g. oral mucosa, feet
• Microscopically:
  • Epidermal vesicular disease
  • Healing displaces lesions more dorsally
  • May become infected and form pustules