Nasal Amyloidosis

• Deposition of amyloid in nasal submucosa of horses
• Not part of generalised amyloidosis
• May extend to larynx
• Nodular of diffuse
• Stenosis may cause obstruction
• Smooth surface, waxy sheen on cut surface
• Macrophages and lymphocytes, giant cells
• May have overlying ulceration of mucosa
• Large firm nodules in alar folds, rostral nasal septum and floor of nasal cavity
• Micro:
  • Deposition of hyaline material in nasal mucosa