Changes

== The Female Hypothalamus ==

== The Female Hypothalamus ==

Foetal ovaries produce oestradiol, but this does NOT defeminize the [[Hypothalamus_- Anatomy & Physiology|Hypothalamus]]. A protein called alpha-fetoprotein binds oestradiol to prevent it from crossing the [[Blood Brain Barrier - Anatomy & Physiology|blood brain barrier]], therefore oestradiol cannot effect the [[Hypothalamus_- Anatomy & Physiology|Hypothalamus]].  Alpha-fetoprotein is synthesized firstly by the embryonic yolk sac and then by the foetal liver.

Foetal ovaries produce oestradiol, but this does NOT defeminize the [[Hypothalamus_- Anatomy & Physiology|hypothalamus]]. A protein called alpha-fetoprotein binds oestradiol to prevent it from crossing the [[Blood Brain Barrier - Anatomy & Physiology|blood brain barrier]], therefore oestradiol cannot affect the hypothalamus.  Alpha-fetoprotein is synthesized firstly by the embryonic yolk sac and then by the foetal liver.

Alpha fetoprotein functions as a foetal blood osmotic regulator and a carrier of fatty acids. As GnRH surges, LH and Oestradiol surge about every 20 days in the female. Surge frequency varies between species and is dependent on the length of their [[Oestrous Cycle - Anatomy & Physiology|oestrous cycles]]. Between surges, there are low amplitude LH pulses.

Alpha fetoprotein functions as a foetal blood osmotic regulator and a carrier of fatty acids. As GnRH surges, LH and oestradiol surge about every 20 days in the female. Surge frequency varies between species and is dependent on the length of their [[Oestrous Cycle - Anatomy & Physiology|oestrous cycles]]. Between surges, there are low amplitude LH pulses.

[[Category:Puberty]][[Category:Developmental Biology]]

[[Category:Puberty]][[Category:Developmental Biology]]

[[Category:To Do - AimeeHicks]][[Category:To Do - Review]]

[[Category:A&P Done]]