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Angiotensin Converting Enzyme (view source)
Revision as of 11:22, 4 January 2011
, 11:22, 4 January 2011no edit summary
Angiotensin converting enzyme is known as '''ACE'''. It is a membrane bound '''metalloproteinase''' and converts Angiotensin 1 to Angiotensin 2.
Angiotensin converting enzyme is known as '''ACE'''. It is a membrane bound '''metalloproteinase''' and converts Angiotensin 1 to Angiotensin 2.
[[Image:angiotensin.jpg|right|thumb|250px|Fvasconcellos 2006, Spacefilling models of angiotensin I (left) and angiotensin II (right).]]
It is very important in the [[Renin Angiotensin Aldosterone System|Renin Angiotensin Aldosterone System (RAAS)]]. ACE is predominantly expressed on epithelial cell membranes in the pulmonary ciculation and this is therefore, the site of action of the ACE inhibitor drugs.
It is very important in the [[Renin Angiotensin Aldosterone System|Renin Angiotensin Aldosterone System (RAAS)]]. ACE is predominantly expressed on epithelial cell membranes in the pulmonary ciculation and this is therefore, the site of action of the ACE inhibitor drugs.