Changes

LCM is an RNA virus from the arenavirus group and is rare in hamsters, although most reported human cases have been associated with infected hamsters. ''In utero'' or perinatal infections may facilitate chronic infection resulting in a progressive wasting disease affecting the liver, spleen, lung, meningies and brain. Approximately 50% of hamsters will clear the infection.

LCM is an RNA virus from the arenavirus group and is rare in hamsters, although most reported human cases have been associated with infected hamsters. ''In utero'' or perinatal infections may facilitate chronic infection resulting in a progressive wasting disease affecting the liver, spleen, lung, meningies and brain. Approximately 50% of hamsters will clear the infection.

<br />

<br />

A common route of infection of LCM in research laboratories is via the transplantation of LCM-containing tumors.Macroscopic pathology may include spenomegally, swollen or shrunken pitted kidneys and hepatomegally. Microscopic pathology may include lymphocytic meningitis, chronic glomerulonephropathy, widespread vasculitis and widespread lymphocytic infiltration.

A common route of infection of LCM in research laboratories is via the transplantation of LCM-containing tumours. Macroscopic pathology may include splenomegally, swollen or shrunken pitted kidneys and hepatomegally. Microscopic pathology may include lymphocytic meningitis, chronic glomerulonephropathy, widespread vasculitis and widespread lymphocytic infiltration.

<br />

<br />