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Limb Development - Anatomy & Physiology (view source)

Revision as of 14:09, 23 January 2011

63 bytes added , 14:09, 23 January 2011

→‎Proximal - Distal Patterning

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===Proximal - Distal Patterning===

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*Governed by the PZ.

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Proximal to distal patterning is governed by the PZ. The first cells to leave the PZ have a proximal identity as these cells have been in the PZ for a shorter amount of time than those that leave the PZ last, which have a distal identity. The "identity" of the cell is achieved by the HOX - A gene expression in that cells that leave the PZ early have fewer HOX - A genes expressed than those which leave later. Less HOX - A gene expression results in a more proximal cell appearance.

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*The first cells to leave the PZ have a proximal identity.

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<br />

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*These cells have been in the PZ for a shorter amount of time than those that leave the PZ last, which have a distal identity.

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*"~~Identity~~" is achieved by the HOX - A gene expression.

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**Cells that leave the PZ early have fewer HOX - A genes expressed than those which leave later.

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**Less HOX - A gene expression results in a more proximal cell appearance.

===Anterior - Posterior Patterning===

Eca02csb

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