Changes

*''E. coli'' is part of the flora of the large intestine, but is not usually found in the small intestine

*''E. coli'' is part of the flora of the large intestine, but is not usually found in the small intestine

*Some strains possess fimbrae which attach the bacteria to the small intestinal epithelium of particular animal species

*Some strains possess fimbrae which attach the bacteria to the small intestinal epithelium of particular animal species

*''E. coli'' may cause diarrhoea via attaching and effacing lesions, where bacteria adhere intimately to the enterocyte, and cause localised effacement of the brush border microvilli; the epithelial erosion causes [[Haemorrhage - Pathology#Dysentery|dysentery]]

*''E. coli'' may cause diarrhoea via attaching and effacing lesions, where bacteria adhere intimately to the enterocyte, and cause localised effacement of the brush border microvilli; the epithelial erosion causes [[Haemorrhage#Dysentery|dysentery]]