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Bones Metabolic - Pathology (view source)

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===[[Gonadal Effect on Bones]]===

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*Oestrogen and androgens

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**Affect growth of skeleton

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**Accelerate epiphyseal closure

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*Oestrogen

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**Stimulates [[Bones - Anatomy & Physiology|osteoblasts]] to produce matrix

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**Inhibits [[Bones - Anatomy & Physiology|osteoclasts]]

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*'''Hypogonadism''' in growing skeleton -> delayed epiphyseal closure and skeletal maturation

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~~[[Category:Bones - Metabolic Pathology]]~~

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