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Porcine Adenomatosis Complex (view source)

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== Diagnosis ==

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~~==== Pathology ====~~

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Clinical signs and history of a closed herd plus signalment of pigs is indicative. On post mortem examination the terminal [[Small Intestine Overview - Anatomy & Physiology|small intestine]] and [[Colon - Anatomy & Physiology|colon]] are affected by proliferation of the mucosal epithelium. Signs will include thickened mucosal epithelium, polypoid-like nodules several millimetres in diameter. there may also be undifferentiated epithelium replaces goblet cells. Its appearance is almost neoplastic. <br>Histologically it will appear similar to a virus induced proliferation. Organisms seen in the apical part of epithelial cells lining glands of terminal [[Ileum - Anatomy & Physiology|ileum]], [[Colon - Anatomy & Physiology|colon]] and [[Caecum - Anatomy & Physiology|caecum]].

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*The terminal [[Small Intestine Overview - Anatomy & ~~Physiology|small intestine]] and [[Colon - Anatomy & Physiology|colon]] are affected by proliferation of the mucosal epithelium.~~

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*'''Gross'''

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**Thickened mucosal epithelium.

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**Has almost polypoid-like nodules several millimetres in diameter.

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**Undifferentiated epithelium replaces goblet cells.

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***Appears almost neoplastic.

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*'''Histologically'''

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**Very similar to a virus induced proliferation.

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**Organisms seen in the apical part of epithelial cells lining glands of terminal [[Ileum - Anatomy & Physiology|ileum]], [[Colon - Anatomy & Physiology|colon]] and [[Caecum - Anatomy & Physiology|caecum]].

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**May produce mild ulceration in mucosa and mild inflammatory infiltration.

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~~==== Sequelae ====~~

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*Resolution.

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*Necrotic enteritis.

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*Secondary chronic infection (regional enteritis).

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*Porcine haemorrhgaic enteritis (PHE).

[[Category:Enteritis,_Proliferative]] [[Category:Intestinal_Diseases_-_Pig]] [[Category:Enteritis,_Bacterial]] [[Category:To_Do_-_Kate]]

Kthompson

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