Changes

== Diagnosis  ==

== Diagnosis  ==

Clinical signs of a failure to thirve and history of a closed herd plus signalment of pigs is indicative. On post mortem examination the terminal [[Small Intestine Overview - Anatomy & Physiology|small intestine]] and [[Colon - Anatomy & Physiology|colon]] are affected by proliferation of the mucosal epithelium. Signs will include thickened mucosal epithelium, polypoid-like nodules several millimetres in diameter. there may also be undifferentiated epithelium replaces goblet cells. Its appearance is almost neoplastic. <br>Histologically it will appear similar to a virus induced proliferation. Organisms seen in the apical part of epithelial cells lining glands of terminal [[Ileum - Anatomy & Physiology|ileum]], [[Colon - Anatomy & Physiology|colon]] and [[Caecum - Anatomy & Physiology|caecum]]. The organism can be stained by silver staining by the use of aintibody in immunofluresence or PCR.

Clinical signs of a failure to thirve and history of a closed herd plus signalment of pigs is indicative. On post mortem examination the terminal [[Small Intestine Overview - Anatomy & Physiology|small intestine]] and [[Colon - Anatomy & Physiology|colon]] are affected by proliferation of the mucosal epithelium. Signs will include thickened mucosal epithelium, polypoid-like nodules several millimetres in diameter. there may also be undifferentiated epithelium replaces goblet cells. Its appearance is almost neoplastic. <br>Histologically it will appear similar to a virus induced proliferation. Organisms seen in the apical part of epithelial cells lining glands of terminal [[Ileum - Anatomy & Physiology|ileum]], [[Colon - Anatomy & Physiology|colon]] and [[Caecum - Anatomy & Physiology|caecum]]. The organism can be stained by silver staining by the use of aintibody in immunofluresence or PCR.

 

 

 

 

Individually affected animals may be treated with tetracyclines parenterally. These animals must be isolated. In affected groups the same treatment can be given via the drinking water.<br>Any new genetic material into the herd should be by A.I. or embryo transfer only so as to reduce risk of introduction of the disease into the herd.

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