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== Synonyms<br> ==
Aujeszky's Disease, Pseudorabies, Mad Itch
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====Pathogenesis====
== Introduction<br> ==
This disease is notifiable and exotic to the UK. It is still present in Ireland and is not notifiable there. It is present worldwide and is partiularly a problem in Eastern Europe. The virus can affect pigs, cattle, horses, cats, dogs and sheep.<br>
The virus affects all animals differently, for instance, in sows, aerosol transmission causes bronchopneumonia followed by viremia, where as in piglats the virus spreads to neurons, causing encephalitis with convulsions. In other animals the air-borne virus can infect a skin wound and cause pruritus (mad itch), followed by encephalitis.<br>
====Control====
The latent virus can reactivated by stress, such as mixing of stock or transport.<br>
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[[Category:Herpesviridae]][[Category:Pig Viruses]][[Category:Respiratory Diseases - Pig]][[Category:Neurological Diseases - Pig]]
== Clinical Signs<br> ==
[[Category:To_Do_-_Clinical/Viruses]]
Clinical signs vary with different species of animal. In sows, where the virus causes bronchopneumonia, signs include coughing, serous nasal discharge, increased respiratory rate, increased lung sounds on auscultation and pyrexia and general malaise. Some sows will recover, but in others the disease will cause abortion and occasionall death. In piglets, signs are much more severe and many die within 2 days. Signs include pyrexia, malaise, severe depression and convulsions. In other animals, signs include a severe pruritus follwed by encephalitis and signs such as convulsions etc.<br>
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== Diagnosis<br> ==
Diagnosis can be by ELISA in order to detect virus antibody.<br>
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== Control<br> ==
. In countries where the disease is endemic, such as Ireland and Europe, there is a vaccine avaliable. These are <span style="font-weight: bold;">g</span>E-deleted '''marker vaccines''' that work by stimulating cell-mediated immunity.
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== References<br> ==
Blood, D.C. and Studdert, V. P. (1999) Saunders Comprehensive Veterinary Dictionary (2nd Edition) Elsevier Science<br>Cowart, R.P. and Casteel, S.W. (2001) An Outline of Swine diseases: a handbook Wiley-Blackwell<br>Jackson, G.G. and Cockcroft, P.D. (2007) Handbook of Pig Medicine Saunders Elsevier<br>Straw, B.E. and Taylor, D.J. (2006) Disease of Swine Wiley-Blackwell<br>Taylor, D.J. (2006) Pig Diseases (Eighth edition) St Edmunsdbury Press ltd<br>
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[[Category:Herpesviridae]] [[Category:Pig_Viruses]] [[Category:Respiratory_Diseases_-_Pig]] [[Category:Neurological_Diseases_-_Pig]] [[Category:To_Do_-_Review]]