Changes

== Introduction  ==

== Introduction  ==

This virus is of the family [[:Category:Paramyxovirinae|paramyxoviridae]] and its virulence varies with isolates. Alone, this virus does not usually produce severe disease in cattle, but with other agents such [[Bovine Respiratory Syncitial Virus]], [[Infectious Bovine Rhinotracheitis]] and bacteria such as [[:Category:Mannheimia and Pasteurella species|''Mannheima'']] and [[:Category:Mycoplasma species|''Mycoplasmas'']], makes up the [[Enzootic Pneumonia - Calves|enzootic pneumonia complex]] which mostly affects calves.  

This virus is of the family [[:Category:Paramyxovirinae|paramyxoviridae]] and its virulence varies with isolates. Alone, this virus does not usually produce severe disease in cattle, but with other agents such [[Bovine Respiratory Syncytial Virus]], [[Infectious Bovine Rhinotracheitis]] and bacteria such as [[:Category:Pasteurella and Mannheimia species|''Mannheimia'']] and [[:Category:Mycoplasmas|''Mycoplasmas'']], makes up the [[Enzootic Pneumonia - Calves|enzootic pneumonia complex]] which mostly affects calves.  

Occurence of the disease is usually thought to be due to stress such as mixing of animals of different age groups, transport and winter housing. Poor hygiene also contributes to this.

Occurence of the disease is usually thought to be due to stress such as mixing of animals of different age groups, transport and winter housing. Poor hygiene also contributes to this.

The virus causes cessation of [[Respiratory System General Introduction - Pathology#Mucociliary_escalator|ciliary clearance]] and epithelial necrosis, which predisposes to secondary bacterial infections and can leading to clinical signs. This occurs due to replication in airway epithelial cells causing an initial [[bronchitis]], which may lead to bronchiolitis and then extension into alveoli, causing [[Bronchointerstitial Pneumonia|bronchointerstitial pneumonia]]. Early stages may show intracytoplasmic inclusions and the resulting exudate is predominantly neutrophilic.  

The virus causes cessation of [[Respiratory System General Introduction - Pathology#Mucociliary_escalator|ciliary clearance]] and epithelial necrosis, which predisposes to secondary bacterial infections and can leading to clinical signs. This occurs due to replication in airway epithelial cells causing an initial [[bronchitis]], which may lead to bronchiolitis and then extension into alveoli, causing [[Bronchointerstitial Pneumonia|bronchointerstitial pneumonia]]. Early stages may show intracytoplasmic inclusions and the resulting exudate is predominantly neutrophilic.

 

== Signalment ==

== Signalment ==