Changes

*'''Renal hyperparathyroidism'''

*'''Renal hyperparathyroidism'''

**Pathogenesis:

**Pathogenesis:

***[[Kidney Renal Failure - Pathology#Chronic|Chronic renal failure]]

***[[Chronic Renal Failure|Chronic renal failure]]

****-> Retention of phosphate (due to reduced glomerular filtration) and inadequate production of vitamin D by kidneys

****-> Retention of phosphate (due to reduced glomerular filtration) and inadequate production of vitamin D by kidneys

*****-> [[Kidney Renal Failure - Pathology#Uraemia|Hyperphosphataemia]] and hypocalcaemia (high P depresses Ca)

*****-> Hyperphosphataemia and hypocalcaemia (high P depresses Ca)

******-> Increased PTH output  

******-> Increased PTH output  

*******-> Increased bone resorption

*******-> Increased bone resorption