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[[Category: To Do - Steph]]
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Also Known As: '''''Enzootic Bovine Leucosis''''' — '''''Bovine Leukosis''''' — '''''EBL''''' — '''''BLV''''' — '''''Bovine Leukemia''''' — '''''Lymphosarcoma''''' — '''''Sporadic Bovine Leukosis''''' — '''''Bovine Malignant Lymphoma'''''
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==Introduction==
 
[[File:BLV.jpeg|thumb|200px|right|Conjunctival prolapse in cow with bovine viral leucosis (sourced from Wikimedia Commons)]]
 
[[File:BLV.jpeg|thumb|200px|right|Conjunctival prolapse in cow with bovine viral leucosis (sourced from Wikimedia Commons)]]
Also Known As — '''''Enzootic Bovine Leucosis''''' — '''''Bovine Leukosis''''' — '''''EBL''''' — '''''BLV''''' — '''''Bovine Leukemia''''' — '''''Lymphosarcoma''''' — '''''Sporadic Bovine Leukosis''''' — '''''Bovine Malignant Lymphoma'''''
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Bovine leukaemia virus is a [[:Category:Retroviridae|'''retrovirus''']] causing two specific diseases: '''Bovine lymphosarcoma''' and '''Persistent lymphocytosis'''.  
 
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=Introduction=
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Bovine leukaemia virus is a '''retrovirus''' causing two specific diseases: '''Bovine lymphosarcoma''' and '''Persistent lymphocytosis'''.  
      
Bovine lymphosarcoma is fatal while persistent lymphocytosis is not usually so.  
 
Bovine lymphosarcoma is fatal while persistent lymphocytosis is not usually so.  
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This disease is '''notifiable''' to the World Organisation for Animal Health ([http://www.oie.int/ OIE])
 
This disease is '''notifiable''' to the World Organisation for Animal Health ([http://www.oie.int/ OIE])
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=Signalment=
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==Signalment==
 
Cattle are thought to be the only species naturally susceptible, and prevalence rates are higher in '''dairy breeds''' than beef.  
 
Cattle are thought to be the only species naturally susceptible, and prevalence rates are higher in '''dairy breeds''' than beef.  
The majority of infected animals are more than 2 years of age, with younger animals developing sporadic bovine leukosis which is thought to be unrelated – see below.
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The majority of infected animals are more than 2 years of age, with younger animals developing [[Sporadic Bovine Leukosis|sporadic bovine leukosis]] which is thought to be unrelated.
    
Sheep are susceptible to experimental infection which appears more pathogenic in this species.
 
Sheep are susceptible to experimental infection which appears more pathogenic in this species.
    
Manifestation of the fatal neoplastic lymphosarcoma form of disease also appears better represented in dairy cattle.
 
Manifestation of the fatal neoplastic lymphosarcoma form of disease also appears better represented in dairy cattle.
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'''Sporadic bovine leucosis''' is seen in young animals and causes thymic and cutaneous lymphosarcome. These animals are usually seronegative for EBL and so the pathogenesis is thought to be different to enzootic bovine leukosis.
      
=Distribution=
 
=Distribution=
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Merck Veterinary Manual, Bovine Leukosis, accessed online 02\06\2011 @ http://www.merckvetmanual.com/mvm/index.jsp?cfile=htm/bc/54800.htm&word=leukosis
 
Merck Veterinary Manual, Bovine Leukosis, accessed online 02\06\2011 @ http://www.merckvetmanual.com/mvm/index.jsp?cfile=htm/bc/54800.htm&word=leukosis
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[[Category:Retroviridae]]
 
[[Category: To Do - CABI review]]
 
[[Category: To Do - CABI review]]
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