Changes

*Bruxism, fine tremors, and hyperaesthesia to sound or sudden movements

*Bruxism, fine tremors, and hyperaesthesia to sound or sudden movements

*Exercise intolerant and develop progressive ataxia (difficulty in turning, swaying on their hind hindquarters and have gait abnormalities such as a high stepping gait in the forelimbs or a bunny hopping gait in the hind limbs)

*Exercise intolerant and develop progressive ataxia (difficulty in turning, swaying on their hind hindquarters and have gait abnormalities such as a high stepping gait in the forelimbs or a bunny hopping gait in the hind limbs)

*Intense pruritis ( compulsive rubbing, nibbling at the skin, or scraping against fixed objects)

*Intense pruritus ( compulsive rubbing, nibbling at the skin, or scraping against fixed objects)

*Wool loss is typically seen over the hindquarters and lateral thorax

*Wool loss is typically seen over the hindquarters and lateral thorax

*Lip smacking or nibbling reflex can often be elicited by scratching over the lumbar region, which is characteristic of scrapie.  

*Lip smacking or nibbling reflex can often be elicited by scratching over the lumbar region, which is characteristic of scrapie.