− | Piglet and weaners suffer from prostration, hind limb stiffness, generalised weakness, muscle facsiculations, retarded growth, depression, excitation, head pressing, circling, hyperaesthesia, abnormal behaviour/aggression and coma. In piglets the disease also causes changes in hair coat (dull/rough), enlarged distended bladder and constipation/reduction in faces or diarrhoea. | + | Piglet and weaners suffer from prostration, hind limb stiffness, generalised weakness, muscle facsiculations, retarded growth, depression, excitation, head pressing, circling, hyperaesthesia, abnormal behaviour/aggression and coma. In piglets the disease also causes changes in hair coat (dull/rough), occular erosions, enlarged distended bladder and constipation/reduction in faces or diarrhoea. |
− | The disease is self limited and closed herds will have sporadic outbreaks of the disease once a herd is infected. The virus can be found in the axon of neurons from it's original site of replication, which is thought to be the nasal mucosa and tonsils. It is also found in tissues such as lung, liver, spleen, kidney, lymph node, heart and testis; suggesting haematopoetic spread. | + | The disease is self limited and closed herds will have sporadic outbreaks of the disease once a herd is infected. The virus can be found in the axon of neurons from it's original site of replication, which is thought to be the nasal mucosa and tonsils. It is also found in tissues such as lung, liver, spleen, kidney, lymph node, heart and testis; suggesting that the virus is spread hematogenously. |