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<FlashCard questions="16">
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<FlashCard questions="17">
|q1=What is Chicken Anaemia Virus Disease also commonly known as?
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|q1=What is ''Chicken anaemia virus disease'' also commonly known as?
 
|a1=
 
|a1=
 
*''Chicken anaemia''
 
*''Chicken anaemia''
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*''Blue wing disease''
 
*''Blue wing disease''
 
|l1=Chicken Anaemia Virus Disease#Introduction
 
|l1=Chicken Anaemia Virus Disease#Introduction
|q2=Which virus causes ''Chicken Anaemia Virus Disease'' and what are it's properties?
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|q2=Which virus causes ''Chicken anaemia virus disease'' and what are it's properties?
 
|a2=
 
|a2=
 
''Chicken anaemia virus'' (CAV):
 
''Chicken anaemia virus'' (CAV):
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*Paresis
 
*Paresis
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*Clinical signs are dependent on the age of the bird.  
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Clinical signs are dependent on the age of the bird. Chicks develop clinical signs within two weeks of hatching if infected via vertical transmission. Chicks older than 14 days old do not show any clinical signs if infected via horizontal transmission.  
*Chicks develop clinical signs within two weeks of hatching if infected via vertical transmission.
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*Chicks older than 14 days old do not show any clinical signs if infected via horizontal transmission.  
   
|l8=Chicken Anaemia Virus Disease#Clinical Signs
 
|l8=Chicken Anaemia Virus Disease#Clinical Signs
|q9=How is ''Chicken anaemia virus disease transmitted?
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|q9=How is ''Chicken anaemia virus disease'' transmitted?
 
|a9=  
 
|a9=  
 
*Horizontally through fomites and faecal-oral as the virus is excreted by a small number of vertically infected hatch mates. This occurs in older chickens that lack maternal derived antibodies.
 
*Horizontally through fomites and faecal-oral as the virus is excreted by a small number of vertically infected hatch mates. This occurs in older chickens that lack maternal derived antibodies.
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*Vertically as chicks hatch from infected layers of naive flocks over a period of 3 to 6 weeks. After this period the breeder layers develop sufficient CAV antibodies to stop the transmission of the virus to the egg.    Clinical signs are seen in 10-14 day old chicks.
 
*Vertically as chicks hatch from infected layers of naive flocks over a period of 3 to 6 weeks. After this period the breeder layers develop sufficient CAV antibodies to stop the transmission of the virus to the egg.    Clinical signs are seen in 10-14 day old chicks.
 
|l9=Chicken Anaemia Virus Disease#Epidemiology
 
|l9=Chicken Anaemia Virus Disease#Epidemiology
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|a10=One
 
|a10=One
 
|l10=Chicken Anaemia Virus Disease#Epidemiology
 
|l10=Chicken Anaemia Virus Disease#Epidemiology
|q11=How can CAV isolates be distinguished?|a11=Restriction endonuclease analysis of amplified DNA.
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|q11=How can CAV isolates be distinguished?
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|a11=Restriction endonuclease analysis of amplified DNA.
 
|l11=Chicken Anaemia Virus Disease#Epidemiology
 
|l11=Chicken Anaemia Virus Disease#Epidemiology
 
|q12=What is the mortality rates within the flock?
 
|q12=What is the mortality rates within the flock?
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*Indirect immunofluorescence
 
*Indirect immunofluorescence
 
|l14=Chicken Anaemia Virus Disease#Diagnosis
 
|l14=Chicken Anaemia Virus Disease#Diagnosis
Post mortem findings include:
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*severe atrophy of the lymphoid organs. The thymus, bursa of Fabricius, and to a lesser extent the spleen are all affected by a depletion of lymphocytes and sequential hyperplasia of reticular cells. Common finding include haemorrhages throughout the skeletal muscle and subcutaneous tissue and pale watery bone marrow. Severe aplasia of the bone marrow occurs and haematopoietic cells are replaced with adipose tissue, giving the bone marrow its watery texture and characteristic change in colour from red to yellow.
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|l14=Chicken Anaemia Virus Disease#Epidemiology
   
|q15=What can be found on postmortem?
 
|q15=What can be found on postmortem?
 
|a15=
 
|a15=
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|q17=How is ''Chicken anaemia virus disease'' controlled?
 
|q17=How is ''Chicken anaemia virus disease'' controlled?
 
|a17=
 
|a17=
Vertical spread is controlled by the vaccination of breeding hens with both live attenuated and wild vaccines that reduces the vertical transmission rate.  
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Vaccination of breeding hens with both live attenuated and wild vaccines reduces the vertical transmission rate.  
    
Wild type vaccines are cheaper but can increase horizontal transmission rates and hidden reduction in production of older birds.  
 
Wild type vaccines are cheaper but can increase horizontal transmission rates and hidden reduction in production of older birds.  
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