Changes

* Pleomorphic epithelial cells - these have a variable appearance from benign keratinized mature squames to epithelial cells with anisocytosis, basophilic cytoplasm and extensive vacuolation.

* Pleomorphic epithelial cells - these have a variable appearance from benign keratinized mature squames to epithelial cells with anisocytosis, basophilic cytoplasm and extensive vacuolation.

* Binucleate cells, chromatin clumping and prominent nucleoli may be present

* Binucleate cells, chromatin clumping and prominent nucleoli may be present

   

   

Any mass suspicious of squamous cell carcinoma should be '''biopsied''' to confirm diagnosis.

Any mass suspicious of squamous cell carcinoma should be '''biopsied''' to confirm diagnosis.