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Small Animal Emergency and Critical Care Medicine Q&A 20 (view source)
Revision as of 13:08, 17 August 2011
, 13:08, 17 August 2011Created page with "[[Image:|centre|500px]] <br /> '''This blood is from a seven-year-old, intact female Labrador Retriever presented for evaluation of weakness. PCV – 9%; TS – 8.0 g/dl.''' <..."
[[Image:|centre|500px]]
<br />
'''This blood is from a seven-year-old, intact female Labrador Retriever presented for evaluation of weakness. PCV – 9%; TS – 8.0 g/dl.'''
<br />
<FlashCard questions="4">
|q1=What test has been performed, and what is the abnormality pictured?
|a1=
Slide test for autoagglutination. Autoagglutination.
|l1=
|q2=What does this abnormality suggest about the etiology of this dog’s anemia?
|a2=
The presence of autoagglutination, when differentiated from rouleaux formation, suggests that this patient’s anemia is immune-mediated in origin.
|l2=
|q3=Is a Coombs’ test necessary to confirm the diagnosis?
|a3=
A positive result in saline slide agglutination negates the need to perform a Coombs’ test.
|l3=
|q4=How would you treat this patient?
|a4=
Treatment of IMHA depends on non-specific suppression of the immune system, with glucocorticoids being the mainstay of therapy.
In dogs with autoagglutination, aggressive treatment with prednisone (2–4 mg/kg p/o bid) and a cytotoxic drug is warranted from the
beginning.
Cyclophosphamide (50 mg/m2 p/o 4 days per week) or azathioprine (2 mg/kg p/o daily for 4 days, then every other day) may be used.
Cyclosporin A (10 mg/kg p/o bid for 10 days) may be used in patients with intravascular hemolysis.
|l4=
</FlashCard>
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[[Category:Small Animal Emergency and Critical Care Medicine Q&A]]
<br />
'''This blood is from a seven-year-old, intact female Labrador Retriever presented for evaluation of weakness. PCV – 9%; TS – 8.0 g/dl.'''
<br />
<FlashCard questions="4">
|q1=What test has been performed, and what is the abnormality pictured?
|a1=
Slide test for autoagglutination. Autoagglutination.
|l1=
|q2=What does this abnormality suggest about the etiology of this dog’s anemia?
|a2=
The presence of autoagglutination, when differentiated from rouleaux formation, suggests that this patient’s anemia is immune-mediated in origin.
|l2=
|q3=Is a Coombs’ test necessary to confirm the diagnosis?
|a3=
A positive result in saline slide agglutination negates the need to perform a Coombs’ test.
|l3=
|q4=How would you treat this patient?
|a4=
Treatment of IMHA depends on non-specific suppression of the immune system, with glucocorticoids being the mainstay of therapy.
In dogs with autoagglutination, aggressive treatment with prednisone (2–4 mg/kg p/o bid) and a cytotoxic drug is warranted from the
beginning.
Cyclophosphamide (50 mg/m2 p/o 4 days per week) or azathioprine (2 mg/kg p/o daily for 4 days, then every other day) may be used.
Cyclosporin A (10 mg/kg p/o bid for 10 days) may be used in patients with intravascular hemolysis.
|l4=
</FlashCard>
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desc none}}
[[Category:Small Animal Emergency and Critical Care Medicine Q&A]]