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Chinchillas (Laboratory) - Pathology (view source)
Revision as of 15:51, 18 August 2011
, 15:51, 18 August 2011→Digestive System
==Digestive System==
==Digestive System==
===''Pseudomonas aeruginosa'' Infection===
This is often a secondary infection due to stress and has been linked to drinking water and the general cage environment. Transmission is via aerosol, fecal-oral routes and via contact between animals. Clinical signs can include anorexia, depression, diarrhoea/constipation, mastitis, intradermal pustules and acute death. This infection is a multifocal systemic infection.
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Macroscopic lesions can include abcesses throughout multiple organs, a generalised lymphadenopathy and generalised multifocal necrosis.
===''Listeria monocytogenes'' Infection===
''L. monocytogenes'' infections are associated with poor sanitation and contaminated feeds and/or water. Tranmission is via the fecal-oral route. Chinchillas appear to be particularly susceptible to this species of bacterium. Clinical signs are consistent with those found with ''P. aeruginosa'' infections (above). Additionally, this infection may also have a neurological element which may include flaccid ears, ataxia, circling and convulsions.
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Macroscopic lesions may include fibrinous peritonitis, broad multifocal mamillary necrosis and widespread intersitial pneumonia. Most organs are susceptible to ''L. monocytogenes''. Microscopic histopathology may include monocytic perivascular cuffing in brain tissues.
===''Yersina'' Infections===
===Iatrogenic (Antibiotics)===
===Iatrogenic (Antibiotics)===
The administration of inappropriate antibiotics such as lincomycin, cephalosporins, penecillins or amoxicillins may result in a decrease in the usual gram-positive gut flora and an increase in gram-negative bacteria causing enterotoxaemia. ''Clostridium perfringens'' is the most common gram-negative causative agent of enterotoxaemia. Clinical signs will include emaciation, diarrhoea, lethargy, dehydration and if untreated, death.
The administration of inappropriate antibiotics such as lincomycin, cephalosporins, penecillins or amoxicillins may result in a decrease in the usual gram-positive gut flora and an increase in gram-negative bacteria causing enterotoxaemia. ''Clostridium perfringens'' is the most common gram-negative causative agent of enterotoxaemia. Clinical signs will include emaciation, diarrhoea, lethargy, dehydration and if untreated, death.