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Chinchillas (Laboratory) - Pathology (view source)
Revision as of 16:47, 18 August 2011
, 16:47, 18 August 2011→Baylisascaris procyonis Infection
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Gross lesions may include multifocal necrosis of the brain. Histopathology may include meningitis with sections containing ascarid larvae within the [[Midbrain_-_Anatomy_%26_Physiology|midbrain]], [[Hindbrain_-_Anatomy_%26_Physiology#Medulla_Oblongata|medulla]] and [[Hindbrain_-_Anatomy_%26_Physiology#Cerebellum_Structure_.26_Function|cerebellum]].
Gross lesions may include multifocal necrosis of the brain. Histopathology may include meningitis with sections containing ascarid larvae within the [[Midbrain_-_Anatomy_%26_Physiology|midbrain]], [[Hindbrain_-_Anatomy_%26_Physiology#Medulla_Oblongata|medulla]] and [[Hindbrain_-_Anatomy_%26_Physiology#Cerebellum_Structure_.26_Function|cerebellum]].
===Protozoal Meningioencephalitis===
Protozoal species including ''Toxoplasma gondii'' and ''Frenkelia sp.'' are associated with meningioencephalitis in chinchilla. Although rare, clinical signs of infection include a purulent nasal discharge, cyanosis, incoordination, depression, weight loss and dyspnea.
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Macroscopic pathological findings may include haemorrhagic lungs and an enlarged spleen. The myocardium, brain, pancreas and intestines may also be grossly enlarged. Microscopic pathological findings may include ''Toxoplasma'' pseudocysts or bradyzoites within the tissue of the lungs, brain, myocardium, pancreas or intestines. Tachyzoites may also be found in blood and/or lymphatic fluids.
===Herpesvirus 1 Infections===
A spontaneous infection with human-type herpesvirus-1 has been reported in chinchillas and clinical signs include recumbancy, disorientation, seizures and progression to death.
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Microscopic pathological findings may include non-supparative meningitis and/or polioencephalitis with associated neuronal necrosis. There may also be intranuclear inclusion bodies primarily affecting the brain stem and cerebral cortex. Ulcerative keratitis, uveitis, retinitis, retinal degeneration, optical neuritis and purulent rhinitis have also been associated with herpesvirus-1.
==Cardiorespiratory System==
==Cardiorespiratory System==