Changes

===Microscopically===

===Microscopically===

The liver exhibits all 3 responses to injury:

The liver exhibits all 3 responses to injury:

:nodular regeneration of the parenchyma - haphazard regeneration of liver cells forming islands of new cells surrounded by condensed portal areas

*nodular regeneration of the parenchyma - haphazard regeneration of liver cells forming islands of new cells surrounded by condensed portal areas

:fibrosis - early cases show areas of [[Liver Fibrosis|fibrosis]] connecting two or more portal triads, later cases have prominent laying down of cartilage.

*fibrosis - early cases show areas of [[Liver Fibrosis|fibrosis]] connecting two or more portal triads, later cases have prominent laying down of cartilage.

:biliary hyperplasia

*biliary hyperplasia

==References ==

==References ==