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*Most virulent replicate in lymphoid cells and neurons ([[Paramyxoviridae#Canine Distemper Virus (CDV)|Distemper]], [[Paramyxoviridae#Newcastle Disease Virus (NDV)|NDV]])
*Most virulent replicate in lymphoid cells and neurons ([[Paramyxoviridae#Canine Distemper Virus (CDV)|Distemper]], [[Paramyxoviridae#Newcastle Disease Virus (NDV)|NDV]])
*Links to the readiness to cleave Fo and Ho precursors in different cells
*Links to the readiness to cleave Fo and Ho precursors in different cells
====Antigenic differentiation====
*Major conserved immunodominant virus-specific antigens on [[Paramyxoviridae#Structure|F and HN]]
**-> Vaccines protect against all isolates of the same virus
*Minor morbillivirus-specific epitopes on [[Paramyxoviridae#Structure|F]]
**Some crossprotectin between [[Paramyxoviridae#Canine Distemper Virus (CDV)|canine distemper]], measels and rinderpest
*Minor variable epitopes of [[Paramyxoviridae#Structure|F, HN and '''NP''']]
**Allows antigenic '''fingerprinting'''
===Canine Distemper Virus (CDV)===
===Canine Distemper Virus (CDV)===