Changes

An outbreak of acute respiratory disease with profuse nasal discharge, fever and depression suggests IBR. In a naive herd, the epidemic progresses quickly and respiratory signs are associated with neonatal deaths and abortions at 4 to 8 months of pregnancy. Hypovirulent strains can circulate without obvious clinical signs. The IPV form is suspected if animals have vesicular and pustular lesions of the genital mucosa and there is evidence of venereal transmission.

An outbreak of acute respiratory disease with profuse nasal discharge, fever and depression suggests IBR. In a naive herd, the epidemic progresses quickly and respiratory signs are associated with neonatal deaths and abortions at 4 to 8 months of pregnancy. Hypovirulent strains can circulate without obvious clinical signs. The IPV form is suspected if animals have vesicular and pustular lesions of the genital mucosa and there is evidence of venereal transmission.

In a laboratory, the '''virus can be isolated from nasal or vaginal swabs''', or from triturated tissue. BHV-1 DNA can also be detected by '''polymerase chain reaction (PCR).'''  

In a laboratory, the '''virus can be isolated from nasal or vaginal swabs''', or from triturated tissue. BHV-1 DNA can also be detected by '''polymerase chain reaction (PCR).''' In an individual animal, '''paired serology''' is useful with a raised antibody response seen two weeks after clinical signs.

'''[[ELISA testing|ELISAs]]''' have also been developed to detect BHV-1 antibodies in '''bulk milk''', or in milk samples from individual cows. Milk ELISAs have been found to perform well when compared with standard serum ELISAs.

'''[[ELISA testing|ELISAs]]''' have also been developed to detect BHV-1 antibodies in '''bulk milk''', or in milk samples from individual cows. Milk ELISAs have been found to perform well when compared with standard serum ELISAs.