Changes

==Diagnosis==

==Diagnosis==

'''Specific monoclonal antibodies''' are available for BHV-5 and can be used with immunoperoxidase staining for confirmatory identification. '''PCR''' is also available.  

'''Specific monoclonal antibodies''' are available for BHV-5 and can be used with immunoperoxidase staining on formalin fixed brain tissue for confirmatory identification. '''PCR''' is also available.  

Antibodies against BHV-5 can be detected using most ''' [[ELISA testing|ELISA kits]] designed for [[Infectious Bovine Rhinotracheitis|BHV-1]] ''' due to their close relationship.  

Antibodies against BHV-5 can be detected using most ''' [[ELISA testing|ELISA kits]] designed for [[Infectious Bovine Rhinotracheitis|BHV-1]] ''' due to their close relationship.  

On post-mortem examination, a '''non-suppurative meningoencephalitis and evident perivascular cuffing'''. Lesions are more pronounced in white matter. '''Necrosis, oedema and spongiosis''' may also be recognisable. In some cases, '''satellitosis''' also develops.  

On post-mortem examination, a '''non-suppurative meningoencephalitis and evident perivascular cuffing'''. Lesions are more pronounced in white matter. '''Necrosis, oedema and spongiosis''' may also be recognisable. In some cases, '''satellitosis''' also develops.

==Treatment==

==Treatment==