Changes

==Clinical Signs==

==Clinical Signs==

'''Presenting signs include''': '''weight loss or muscle wasting''', decreased muscle tone, abnormal bulging of supraorbital fat pads: catabolism promoted

'''Presenting signs include''': '''weight loss or muscle wasting''', decreased muscle tone, abnormal bulging of supraorbital fat pads.

A '''thick, long and wavy hair coat''' with an abnormal shedding pattern is evident in 85% of affected horses. This sign is often preceded by months to years of subtle coat variations, such as patchy slow shedding during late spring or delayed shedding with alopecia.

A '''thick, long and wavy hair coat''' with an abnormal shedding pattern is evident in 85% of affected horses. This sign is often preceded by months to years of subtle coat variations, such as patchy slow shedding during late spring or delayed shedding with alopecia.

'''Chronic recurrent skin, pulmonary, urinary, or sinus infections''': due to immunosuppression

'''Chronic recurrent skin, pulmonary, urinary, or sinus infections''': due to immunosuppression

'''Vision disturbances''': central effects

'''Vision disturbances''': due to pressure of the expanding pituitary mass on the optic nerve.

==Diagnosis==

==Diagnosis==