Changes

While cell-mediated immunity is important in tissue infections, such as Leishmania, specific antibodies are important in controlling parasites that live in the bloodstream, e.g. malaria. Mechanisms of antibody-mediated immunity include:

While cell-mediated immunity is important in tissue infections, such as Leishmania, specific antibodies are important in controlling parasites that live in the bloodstream, e.g. malaria. Mechanisms of antibody-mediated immunity include:

*Directly damaging protozoa

*Directly damaging protozoa

*Activating complement

*Activating [[Complement|complement]], and the subsequent Membrane Attack Complex

*Blocking attachment to host cells

*Blocking attachment to host cells

*Enhancing macrophage phagocytosis

*Enhancing macrophage phagocytosis