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While cell-mediated immunity is important in tissue infections, such as Leishmania, specific antibodies are important in controlling parasites that live in the bloodstream, e.g. malaria. Mechanisms of antibody-mediated immunity include:
 
While cell-mediated immunity is important in tissue infections, such as Leishmania, specific antibodies are important in controlling parasites that live in the bloodstream, e.g. malaria. Mechanisms of antibody-mediated immunity include:
 
*Directly damaging protozoa
 
*Directly damaging protozoa
*Activating complement
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*Activating [[Complement|complement]], and the subsequent Membrane Attack Complex
 
*Blocking attachment to host cells
 
*Blocking attachment to host cells
 
*Enhancing macrophage phagocytosis
 
*Enhancing macrophage phagocytosis
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