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=Staphylococcus=
*Gram positive cocci
==Staphylococcus hyicus==
*Pigs - greasy pig disease
*Exudative epidermitis due to ''Staphylococcus hyicus'' is a worldwide problem in piglets.
*The organism can often be isolated from the mucosa and skin of healthy adult pigs, and can persist in the environment for long periods.
*Disease occurs only in young piglets up to about 35 days of age.
*Passive transfer of antibodies from immune sows and development of immunity with age appear to adequately protect against disease.
*Piglets from non-immune sows are predisposed.
*Skin trauma, such as due to fighting, allowing entry of infective organisms is also considered a risk factor in this disease.
===Pathogenesis===
*''Staphylococcus hyicus'' produces an exfoliative toxin of approximately 30 kDa that causes separation of cells in the upper stratum spinosum resulting in rapid intraepidermal spread of organisms.
*Death of affected piglets is common and is attributed to dehydration, septicemia, or both.
*This porcine disorder has been likened to “scalded skin syndrome” in human neonates, due to skin infection by exfoliative toxin-producing ''Staphylococcus aureus''.
===Differential diagnosis===
*mange (Sarcoptes scabiei var. suis)
*swine parakeratosis (zinc and essential fatty acid deficiency)
*porcine juvenile pustular psoriasiform dermatitis (collarettes or rings typically on the ventrum of young pigs)
*dermatosis vegetans (associated with a giant cell pneumonia)
*dermatophytosis (most commonly Microsporum nanum)
*Gram positive cocci
==Staphylococcus hyicus==
*Pigs - greasy pig disease
*Exudative epidermitis due to ''Staphylococcus hyicus'' is a worldwide problem in piglets.
*The organism can often be isolated from the mucosa and skin of healthy adult pigs, and can persist in the environment for long periods.
*Disease occurs only in young piglets up to about 35 days of age.
*Passive transfer of antibodies from immune sows and development of immunity with age appear to adequately protect against disease.
*Piglets from non-immune sows are predisposed.
*Skin trauma, such as due to fighting, allowing entry of infective organisms is also considered a risk factor in this disease.
===Pathogenesis===
*''Staphylococcus hyicus'' produces an exfoliative toxin of approximately 30 kDa that causes separation of cells in the upper stratum spinosum resulting in rapid intraepidermal spread of organisms.
*Death of affected piglets is common and is attributed to dehydration, septicemia, or both.
*This porcine disorder has been likened to “scalded skin syndrome” in human neonates, due to skin infection by exfoliative toxin-producing ''Staphylococcus aureus''.
===Differential diagnosis===
*mange (Sarcoptes scabiei var. suis)
*swine parakeratosis (zinc and essential fatty acid deficiency)
*porcine juvenile pustular psoriasiform dermatitis (collarettes or rings typically on the ventrum of young pigs)
*dermatosis vegetans (associated with a giant cell pneumonia)
*dermatophytosis (most commonly Microsporum nanum)